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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 25.76
Human Site: Y545 Identified Species: 43.59
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 Y545 K V Q M P P S Y L D T E S T S
Chimpanzee Pan troglodytes XP_531552 2298 258112 Y545 K V Q M P P S Y L D T E S T S
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 Y533 K V Q M P P S Y L D T E S T S
Dog Lupus familis XP_544874 2297 257913 Y545 K V Q M P P S Y L D M E P T S
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 Y545 K V Q M P P S Y L D L E P S S
Rat Rattus norvegicus XP_001055500 2294 257490 S544 S K V Q M P P S Y L D M E P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 Y545 K V Q M P P A Y L D I E S G S
Chicken Gallus gallus XP_001232723 2283 257889 Y543 K V Q M P P S Y L D I E T G S
Frog Xenopus laevis Q642P2 2270 256829 M541 K V L S K V Q M P P A F L D M
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 S568 N S L E K S K S D S R L N Q F
Honey Bee Apis mellifera XP_395999 2434 273219 K532 E K N E L E T K L D T I T T T
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 Q622 A I E H E R S Q T D A C L S Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 L32 R A N V E R A L E R F D S V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 6.6 N.A. 80 80 13.3 0 N.A. 0 26.6 13.3 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 13.3 N.A. 86.6 86.6 13.3 0 N.A. 6.6 53.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 15 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 65 8 8 0 8 0 % D
% Glu: 8 0 8 15 15 8 0 0 8 0 0 50 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 15 8 0 0 0 % I
% Lys: 58 15 0 0 15 0 8 8 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 0 8 0 0 8 58 8 8 8 15 0 0 % L
% Met: 0 0 0 50 8 0 0 8 0 0 8 8 0 0 8 % M
% Asn: 8 0 15 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 50 58 8 0 8 8 0 0 15 8 0 % P
% Gln: 0 0 50 8 0 0 8 8 0 0 0 0 0 8 8 % Q
% Arg: 8 0 0 0 0 15 0 0 0 8 8 0 0 0 0 % R
% Ser: 8 8 0 8 0 8 50 15 0 8 0 0 36 15 50 % S
% Thr: 0 0 0 0 0 0 8 0 8 0 29 0 15 36 22 % T
% Val: 0 58 8 8 0 8 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _